Contents of Mechanics
of Motor Proteins and the Cytoskeleton
1
Introduction 1
PART
I Physical Principles 7
2
Mechanical Forces 9
3
Mass, Stiffness, and Damping of Proteins 29
4
Thermal Forces and Diffusion 49
5
Chemical Forces 75
6
Polymer Mechanics 99
PART
II Cytoskeleton 117
7
Structures of Cytoskeletal Filaments 119
8
Mechanics of the Cytoskeleton 135
9
Polymerization of Cytoskeletal Filaments 151
10
Force Generation by Cytoskeletal Filaments 165
11
Active Polymerization 179
PART
III Motor Proteins 195
12
Structures of Motor Proteins 97
13
Speeds of Motors 213
14
ATP Hydrolysis 229
15
Steps and Forces 245
16
Motility Models: From Crossbridges to Motion 263
Afterword
285
Appendix
287
Bibliography
339
Index
361